Unilateral Agenesis of the Internal Carotid Artery: A Report of Two Rare Cases
DOI:
https://doi.org/10.31661/gmj.v11i.2318Abstract
Background: Internal carotid artery (ICA) agenesis occurs when one or both of the blood vessels that supply blood to the brain do not develop. Congenital agenesis of the ICA rarely occurs. It is usually asymptomatic but may sometimes associate with neurological symptoms such as migraine and pulsatile tinnitus. Moreover, differentiating it from occlusion of ICA is important in patients with stroke. Case Report: We report two cases (63-years-old man and 69-year-old woman) of asymptomatic unilateral ICA agenesis who were referred to our cardiovascular hospital for coronary artery bypass graft. Due to a suspicious history of transient ischemic attack, the patients underwent carotid ultrasonography. With findings suggestive of unilateral ICA agenesis at color Doppler, patients underwent computed tomography angiography that confirmed the diagnosis. Conclusion: Suspecting ICA agenesis at color Doppler imaging of the neck and differentiating it from occluded ICA at CT angiography is important for correct diagnosis and management of the patients.
References
Okawa M, Higashi T, Komiyama M, Fukuda K, Abe H, Inoue T. Left internal carotid artery agenesis with trans-sellar collateral and a right aortic arch: Case report. Interv Neuroradiol. 2015;21(6):759-64.
https://doi.org/10.1177/1591019915609130
PMid:26472640 PMCid:PMC4757351
Oz II, Serifoglu I, Yazgan O, Erdem Z. Congenital absence of internal carotid artery with intercavernous anastomosis: Case report and systematic review of the literature. Interv Neuroradiol. 2016;22(4):473-80.
https://doi.org/10.1177/1591019916641317
PMid:27091873 PMCid:PMC4984390
Oliveira GD, Soares NL, Oliveira GD, Vale BP. Bilateral internal carotid artery agenesis: a case report. Jornal Vascular Brasileiro. 2014;13:336-9.
https://doi.org/10.1590/1677-5449.0046
Lee JH, Oh CW, Lee SH, Han DH. Aplasia of the internal carotid artery. Acta Neurochir (Wien). 2003;145(2):117-25.
https://doi.org/10.1007/s00701-002-1046-y
PMid:12601459
Wani A, Behari S, Lyndoh B, Jaiswal A, Sahu R, Jain V. Multiple aneurysms associated with agenesis of internal carotid artery. Turk Neurosurg. 2011;21(1):83-5.
Given CA 2nd, Huang-Hellinger F, Baker MD, Chepuri NB, Morris PP. Congenital absence of the internal carotid artery: case reports and review of the collateral circulation. AJNR Am J Neuroradiol. 2001;22(10):1953-9.
Li S, Hooda K, Gupta N, Kumar Y. Internal carotid artery agenesis: A case report and review of literature. Neuroradiol J. 2017;30(2):186-91.
https://doi.org/10.1177/1971400918757090
https://doi.org/10.1177/1971400917692162
PMid:28424012 PMCid:PMC5433594
Lie TA, Hage J. Congenital anomalies of the carotid arteries. Plastic and Reconstructive Surgery. 1968;42(3):283.
https://doi.org/10.1097/00006534-196809000-00046
Ryan FH, Kline LB, Gomez C. Congenital Horner's syndrome resulting from agenesis of the internal carotid artery. Ophthalmology. 2000;107(1):185-8.
https://doi.org/10.1016/S0161-6420(99)00006-8
PMid:10647740
Singer R, Ogilvy C. Rordorf. Screening for intracranial aneurysm. Waltham: UpToDate; 2017.
Zink WE, Komotar RJ, Meyers PM. Internal carotid aplasia/hypoplasia and intracranial saccular aneurysms: series of three new cases and systematic review of the literature. J Neuroimaging. 2007;17(2):141-7.
https://doi.org/10.1111/j.1552-6569.2007.00092.x
PMid:17441835
Dinç H, Alioglu Z, Erdöl H, Ahmetoglu A. Agenesis of the internal carotid artery associated with aortic arch anomaly in a patient with congenital Horner's syndrome. AJNR Am J Neuroradiol. 2002;23(6):929-31.
Weon YC, Chung JI, Kim HJ, Byun HS. Agenesis of bilateral internal carotid arteries and posterior fossa abnormality in a patient with facial capillary hemangioma: presumed incomplete phenotypic expression of PHACE syndrome. AJNR Am J Neuroradiol. 2005;26(10):2635-9.
Ottaviano G, Calzolari F, Martini A. Goldenhar syndrome in association with agenesia of the internal carotid artery. Int J Pediatr Otorhinolaryngol. 2007;71(3):509-12.
https://doi.org/10.1016/j.ijporl.2006.11.003
PMid:17161873
Jaeger HJ, Mehring UM, Gissler HM, Mathias KD. Congenital absence of the internal carotid artery and the basilar artery with persistent trigeminal artery associated with coarctation of the aorta. Eur Radiol. 2000;10(11):1805-9.
https://doi.org/10.1007/s003300000500
PMid:11097410
Braga M, Pederzoli M, Beretta S, Ferrarini M, Canovaro P, Arpaia G, Crespi V. Agenesis of the right internal carotid artery and Klippel-Feil syndrome: case report. Spine (Phila Pa 1976). 2009;34(20):E740-2.
https://doi.org/10.1097/BRS.0b013e3181b41181
PMid:19752694
Inamo Y, Harada K. Agenesis of the internal carotid artery and congenital pituitary hypoplasia: proposal of a cause of congenital hypopituitarism. Eur J Pediatr. 2003;162(9):610-2.
https://doi.org/10.1007/s00431-003-1272-1
PMid:12856176
Moon WJ, Porto L, Lanfermann H, Weis R, Zanella FE. Agenesis of internal carotid artery associated with congenital anterior hypopituitarism. Neuroradiology. 2002;44(2):138-42.
https://doi.org/10.1007/s002340100678
PMid:11942366
Stagi S, Traficante G, Lapi E, Pantaleo M, Becciani S, Mortilla M, Seminara S, de Martino M. Agenesis of internal carotid artery associated with isolated growth hormone deficiency: a case report and literature review. BMC Endocr Disord. 2015;15:58.
https://doi.org/10.1186/s12902-015-0037-y
PMid:26481254 PMCid:PMC4617709
Erdogan M, Senadim S, Ince Yasinoglu KN, Selcuk HH, Atakli HD. Internal Carotid Artery Agenesis with an Intercavernous Anastomosis: A Rare Case. J Stroke Cerebrovasc Dis. 2017;26(10):2442-5.
https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.06.055
PMid:28781055
Dinç H, Gümele HR, Kuzeyli K, Baykal S. Unilateral Agenesis of Internal Carotid Artery with Subarachnoid Hemorrhage: Report of Two Cases. Int J Angiol. 1999;8(3):157-60.
https://doi.org/10.1007/s005479900164
https://doi.org/10.1007/BF01616445
PMid:10387124
Kahraman AS, Kahraman B, Ozdemir ZM, Dogan M, Kaya M, Gormeli CA, Durak MA. Congenital Agenesis of Right Internal Carotid Artery: A Report of Two Cases. J Belg Soc Radiol. 2016;100(1):48.
https://doi.org/10.5334/jbr-btr.1015
PMid:30151456 PMCid:PMC6100634
Kumaresh A, Vasanthraj PK, Chandrasekharan A. Unilateral agenesis of internal carotid artery with intercavernous anastomosis: a rare case report. J Clin Imaging Sci. 2015;5:7.
https://doi.org/10.4103/2156-7514.150453
PMid:25806142 PMCid:PMC4322372
Dias EL, da Silveira Filho LG, Ferreira AF. Agenesis of the internal carotid artery: a rare anomaly. Radiol Bras. 2018;51(6):410-1.
https://doi.org/10.1590/0100-3984.2017.0070
PMid:30559562 PMCid:PMC6290750
Martinez M, Desbordes P, Diawara A, Houeze R, Laurent C, Jacquin J. Agenesis of Internal Carotid Artery and Ischemic Stroke, One Case Report: A Review of Literature. Open Access Library Journal. 2018;5(10):1-9.
https://doi.org/10.4236/oalib.1104947
Steer AC, Rowe PW. Bilateral agenesis of the internal carotid artery: case report and approach to management. J Paediatr Child Health. 2008;44(9):511-3.
https://doi.org/10.1111/j.1440-1754.2008.01357.x
PMid:18928467
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Galen Medical Journal
This work is licensed under a Creative Commons Attribution 4.0 International License.