Examination of a Novel Nanocompositer's Bioactivity for Use in Dentistry: Examination of a Novel Nanocompositer's Bioactivity for Use in Dentistry

Sarvenaz Amanolahi Baharvand; Pardis Chaboki; Fateme Pourhatami; Mohamad Milad Shirvandehi; Reza Yusofvand; Payam Ali –Khiavi; Mohammad Shabestari Khiabani; Khadije Yousefi; Paria Ganji Nataj; Paria Arjmandi Sarvestani; Sepideh KarkonShayan; Reza Akhavan-Sigari

doi:10.31661/gmj.v13iSP1.3663

Authors

Sarvenaz Amanolahi Baharvand Faculty of Pharmacy, Mazandaran University of Medical Sciences, Mazandaran, Iran
Pardis Chaboki School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Fateme Pourhatami Department of Basic Science, Faculty of Pharmacy, Pharmaceutical Sciences Branch, Islamic Azad University, Tehrani, Iran
Mohamad Milad Shirvandehi Department of Microbiology, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran
Reza Yusofvand Department of Exceptional Talents , Faculty of Medicine Sciences , Lorestan University of Medical Sciences , Khorramabad , Iran
Payam Ali –Khiavi School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Mohammad Shabestari Khiabani Dentistry faculty, Tabriz University of Medical Sciences, Tabriz, Iran
Khadije Yousefi Department of Materials Science and Engineering, School of Engineering, Yasouj University, Yasouj, Iran
Paria Ganji Nataj Dalian medical University, dalian, china
Paria Arjmandi Sarvestani Department of Biomedical Engineering, Faculty of Engineering, Zand Institute of Higher Education, Shiraz, Iran
Sepideh KarkonShayan Student Research Committee, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran
Reza Akhavan-Sigari Department of Health Care Management and Clinical Research, Collegium Humanum Warsaw Management University Warsaw, Poland

DOI:

https://doi.org/10.31661/gmj.v13iSP1.3663

Keywords:

Nanocomposite; Nano Fast Cement; Setting Time; Nano Hydroxyapatite; Bioactivity

Abstract

The extended setting time of mineral trioxide aggregate (MTA) is one of its primary drawbacks. An alternative to MTA, Nano Fast Cement (NFC) is a novel nanocomposite with a quick setting time. In order to develop an exceptional dental filler, hydroxyapatite nanoparticles (NHA) were introduced to NFC to examine its impact on setting time, biocompatibility, and bioactivity qualities. X-ray diffraction, scanning electron microscopy, Gilmore needle, and MTT assay were used to evaluate the specimens with 0, 10, and 20 W% hydroxyapatite. The antibacterial evaluation was conducted using Enterococcus faecalis (PTCC 1394). Using phase and microstructural studies, the production of hydroxyapatite was discovered. Both 10 and 20 weight percent prime apatite enhanced the specimens' bioactivity and markedly decreased their toxicity behavior. More HA content resulted in greater bioactivity enhancement and toxicity decrease. These results suggest that the physical properties of NFC were not negatively impacted by the addition of NHA. In vitro, they enhanced the filler's bioactivity.

Examination of a Novel Nanocompositer's Bioactivity for Use in Dentistry