The Role of Guided Bone Regeneration in Enhancing Dental Implant Success

Guided Bone Regeneration in Dental Implant

Authors

  • Emad Taghizadeh Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Shahed University, Tehran, Iran
  • Sahar Negargar Department of Dentistry, Asad Abadi Hospital, Tabriz, Iran
  • Kosar Nuroozi Larki Department of Restorative Dentistry, School of Dentistry, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
  • Raman Saberi Haghighi Department of Dentistry, Tehran Univerdity of Medical Sciences, Tehran, Iran
  • Hossein Shahoon Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Shahed University, Tehran, Iran

Keywords:

Guided Bone Regeneration; Dental Implants; Bone Augmentation; Implant Success Rate; Dental Surgery

Abstract

Guided Bone Regeneration (GBR) has become an essential technique in dental implantology, particularly for cases with compromised bone volume that impact implant success. This narrative review examines the role of GBR in enhancing dental implant outcomes, focusing on its applications, biological principles, materials, and clinical protocols. GBR utilizes barrier membranes and bone graft materials to foster bone regeneration in deficient areas, creating a stable foundation for implant placement by preventing soft tissue invasion and promoting osteogenic activity. Through a literature review of recent studies, we assess the clinical efficacy of GBR in addressing bone insufficiencies resulting from periodontal disease, trauma, or resorption following tooth loss, with a particular emphasis on how GBR augments implant stability and long-term survival. The review explores various GBR materials, including resorbable and non-resorbable membranes, and graft types such as autografts, allografts, xenografts, and synthetic options. Additionally, advancements in bioactive membranes, growth factor-enhanced materials, and 3D-printed scaffolds are discussed for their potential to improve regenerative outcomes and reduce procedural complications. Best practices in clinical protocols, including preoperative planning, precise membrane placement, and post-operative care, are analyzed to highlight factors that enhance GBR success. Comparative analyses indicate that GBR significantly improves implant survival and reduces marginal bone loss, demonstrating its efficacy in complex cases. Despite its high success rate, GBR has limitations, such as the potential for complications like peri-implantitis and membrane exposure. The paper concludes with suggestions for future research on optimizing GBR materials, enhancing biological responses, and improving long-term outcomes to broaden its application in dental implantology. This review serves as a resource for clinicians and researchers seeking to maximize implant success through advanced GBR techniques.

References

Simoni E, Isufi R, Kadaifciu D. Guided Bone Regeneration Effects on Bone Quantity and Outcomes of Dental Implants in Patients With Insufficient Bone Support: A Single-Center Observational Study. Cureus. 2023;15(5):e38988.

Yang Z, Wu C, Shi H, Luo X, Sun H, Wang Q et al. Advances in Barrier Membranes for Guided Bone Regeneration Techniques. Frontiers in Bioengineering and Biotechnology. 2022;10:921576.

https://doi.org/10.3389/fbioe.2022.921576

PMid:35814003 PMCid:PMC9257033

Yang R, Zhang S, Song SQ, Liu XD, Zhao G, Zheng J, et al. [Influence of guided bone regeneration on marginal bone loss of implants in the mandible posterior region. a 10-year retrospective cohort study]. 2021;56(12):1211-6.

Simion M, Dahlin C, Rocchietta I, Stavropoulos A, Sánchez RA, Karring TJCoir. Vertical ridge augmentation with guided bone regeneration in association with dental implants. an experimental study in dogs. 2007;18 (1):86-94.

https://doi.org/10.1111/j.1600-0501.2006.01291.x

PMid:17224028

Elgali I, Omar O, Dahlin C, Thomsen P. Guided bone regeneration: materials and biological mechanisms revisited. European Journal of Oral Sciences. 2017;125:315-37.

https://doi.org/10.1111/eos.12364

PMid:28833567 PMCid:PMC5601292

Gentile P, Chiono V, Tonda-Turo C, Ferreira AM, Ciardelli G. Polymeric membranes for guided bone regeneration. Biotechnology journal. 2011;6(10):1187-97.

https://doi.org/10.1002/biot.201100294

PMid:21932249

Rakhmatia YD, Ayukawa Y, Furuhashi A, Koyano K. Current barrier membranes: Titanium mesh and other membranes for guided bone regeneration in dental applications. Journal of Prosthodontic Research. 2013;57(1):3-14.

https://doi.org/10.1016/j.jpor.2012.12.001

PMid:23347794

Schwarz F, Rothamel D, Herten M, Wuestefeld M, Sager M, Ferrari D et al. Immunohistochemical characterization of guided bone regeneration at a dehiscence-type defect using different barrier membranes: an experimental study in dogs. Clinical Oral Implants Research. 2008;19(4):402-15.

https://doi.org/10.1111/j.1600-0501.2007.01486.x

PMid:18324961

Turri A, Elgali I, Vazirisani F, Johansson A, Emanuelsson L, Dahlin C et al. Guided bone regeneration is promoted by the molecular events in the membrane compartment. Biomaterials. 2016;84:167-83.

https://doi.org/10.1016/j.biomaterials.2016.01.034

PMid:26828682

Kim K, Su Y, Kucine AJ, Cheng K, Zhu D. Guided Bone Regeneration Using Barrier Membrane in Dental Applications. ACS Biomaterials Science & Engineering. 2023;9(10):5457-78.

https://doi.org/10.1021/acsbiomaterials.3c00690

PMid:37650638

Miller RJ, Korn RJ, Miller RJJTIjop, dentistry r. The Use of a Dehydrated, Deepithelialized Amnion-Chorion Membrane in Guided Bone Regeneration Involving Staged Implant Placement. Case Series with a 5-Year Follow-up. 2021;41(5):657-62.

https://doi.org/10.11607/prd.5602

PMid:34547066

Sanz M, Dahlin C, Apatzidou D, Artzi Z, Bozic D, Calciolari E et al. Biomaterials and regenerative technologies used in bone regeneration in the craniomaxillofacial region: Consensus report of group 2 of the 15th European Workshop on Periodontology on Bone Regeneration. Journal of Clinical Periodontology. 2019;46(S21):82-91.

https://doi.org/10.1111/jcpe.13123

PMid:31215114

Jung RE, Brügger LV, Bienz SP, Hüsler J, Hämmerle CHF, Zitzmann NU. Clinical and radiographical performance of implants placed with simultaneous guided bone regeneration using resorbable and nonresorbable membranes after 22-24 years, a prospective, controlled clinical trial. Clinical Oral Implants Research. 2021;32(12):1455-65.

https://doi.org/10.1111/clr.13845

PMid:34543460 PMCid:PMC9293322

Norowski Jr PA, Fujiwara T, Clem WC, Adatrow PC, Eckstein EC, Haggard WO et al. Novel naturally crosslinked electrospun nanofibrous chitosan mats for guided bone regeneration membranes: material characterization and cytocompatibility. Journal of tissue engineering and regenerative medicine. 2015;9(5):577-83.

https://doi.org/10.1002/term.1648

PMid:23166109

Urban IA, Jovanovic SA, Lozada JJTIjoo, implants m. Vertical ridge augmentation using guided bone regeneration (GBR) in three clinical scenarios prior to implant placement: a retrospective study of 35 patients 12 to 72 months after loading. International Journal of Oral & Maxillofacial Implants. 2009;24(3):502-10.

Işık G, Özden Yüce M, Koçak-Topbaş N, Günbay T. Guided bone regeneration simultaneous with implant placement using bovine-derived xenograft with and without liquid platelet-rich fibrin: a randomized controlled clinical trial. Clinical Oral Investigations. 2021;25(9):5563-75.

https://doi.org/10.1007/s00784-021-03987-5

PMid:34047835

Lee S-W, Kim S-G, Balázsi C, Chae W-S, Lee H-O. Comparative study of hydroxyapatite from eggshells and synthetic hydroxyapatite for bone regeneration. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2012;113(3):348-55.

https://doi.org/10.1016/j.tripleo.2011.03.033

PMid:22676827

Lee J-H, An H-w, Im J-S, Kim W-J, Lee D-W, Yun J-H. Evaluation of the clinical and radiographic effectiveness of treating peri-implant bone defects with a new biphasic calcium phosphate bone graft: a prospective, multicenter randomized controlled trial. Journal of Periodontal & Implant Science. 2023;53(4):306.

https://doi.org/10.5051/jpis.2300640032

PMid:37524378 PMCid:PMC10465810

Park S-Y, Kim K-H, Kim S, Lee Y-M, Seol Y-J. BMP-2 Gene Delivery-Based Bone Regeneration in Dentistry. Pharmaceutics. 2019;11(8):393.

https://doi.org/10.3390/pharmaceutics11080393

PMid:31387267 PMCid:PMC6723260

Mijiritsky E, Assaf HD, Kolerman R, Mangani L, Ivanova V, Zlatev S. Autologous Platelet Concentrates (APCs) for Hard Tissue Regeneration in Oral Implantology, Sinus Floor Elevation, Peri-Implantitis, Socket Preservation, and Medication-Related Osteonecrosis of the Jaw (MRONJ): A Literature Review. Biology. 2022;11(9):1254.

https://doi.org/10.3390/biology11091254

PMid:36138733 PMCid:PMC9495871

Zhang X, Li Q, Wang Z, Zhou W, Zhang L, Liu Y et al. Bone regeneration materials and their application over 20 years: A bibliometric study and systematic review. Frontiers in Bioengineering and Biotechnology. 2022;10:1-19.

https://doi.org/10.3389/fbioe.2022.921092

PMid:36277397 PMCid:PMC9581237

Marshall KM, Wojciechowski JP, Jayawarna V, Hasan A, Echalier C, Øvrebø Ø et al. Bioactive coatings on 3D printed scaffolds for bone regeneration: Translation from in vitro to in vivo models and the impact of material properties and growth factor concentration. bioRxiv. 2023; :2023-10.

https://doi.org/10.1101/2023.10.22.560309

El-Rashidy AA, Roether JA, Harhaus L, Kneser U, Boccaccini AR. Regenerating bone with bioactive glass scaffolds: A review of in vivo studies in bone defect models. Acta Biomaterialia. 2017;62:1-28.

https://doi.org/10.1016/j.actbio.2017.08.030

PMid:28844964

Fitzpatrick V, Martín-Moldes Z, Deck A, Torres-Sanchez R, Valat A, Cairns D et al. Functionalized 3D-printed silk-hydroxyapatite scaffolds for enhanced bone regeneration with innervation and vascularization. Biomaterials. 2021;276:120995.

https://doi.org/10.1016/j.biomaterials.2021.120995

PMid:34256231 PMCid:PMC8408341

Lee J, Lee S, Ahmad T, Madhurakkat Perikamana SK, Lee J, Kim EM et al. Human adipose-derived stem cell spheroids incorporating platelet-derived growth factor (PDGF) and bio-minerals for vascularized bone tissue engineering. Biomaterials. 2020;255:120192.

https://doi.org/10.1016/j.biomaterials.2020.120192

PMid:32559565

Jang J, Longoni A, Li J, Lindberg Gabriella CJ, Rnjak-Kovacina J, Wise Lyn M et al. Strategies for inclusion of growth factors into 3D printed bone grafts. Essays in Biochemistry. 2021;65(3):569-85.

https://doi.org/10.1042/EBC20200130

PMid:34156062

Oliveira ÉR, Nie L, Podstawczyk D, Allahbakhsh A, Ratnayake J, Brasil DL et al. Advances in Growth Factor Delivery for Bone Tissue Engineering. International Journal of Molecular Sciences. 2021;22(2):903.

https://doi.org/10.3390/ijms22020903

PMid:33477502 PMCid:PMC7831065

Nayak VV, Slavin BV, Bergamo ETP, Torroni A, Runyan CM, Flores RL et al. Three-Dimensional Printing Bioceramic Scaffolds Using Direct-Ink-Writing for Craniomaxillofacial Bone Regeneration. Tissue Engineering Part C: Methods. 2023;29(7):332-45.

https://doi.org/10.1089/ten.tec.2023.0082

PMid:37463403 PMCid:PMC10495199

De Bruyckere T, Cabeza RG, Eghbali A, Younes F, Cleymaet R, Cosyn J. A randomized controlled study comparing guided bone regeneration with connective tissue graft to reestablish buccal convexity at implant sites: A 1-year volumetric analysis. Clinical Implant Dentistry and Related Research. 2020;22(4):468-76.

https://doi.org/10.1111/cid.12934

PMid:32686234

Sadek K, El Moshy S, Radwan I, Rady D, Abbass M, El-Rashidy A et al. Molecular Basis beyond Interrelated Bone Resorption/Regeneration in Periodontal Diseases: A Concise Review. International Journal of Molecular Sciences. 2023;24(5):4599.

https://doi.org/10.3390/ijms24054599

PMid:36902030 PMCid:PMC10003253

Li P, Zhu H, Huang D. Autogenous DDM versus Bio‐Oss granules in GBR for immediate implantation in periodontal postextraction sites: A prospective clinical study. Clinical Implant Dentistry and Related Research. 2018;20(6):923-8.

https://doi.org/10.1111/cid.12667

PMid:30230681

Nigmatov IO, Boymuradov SA, Djuraev JA, Shukhratovich YSJTAJoMS, Research P. Post-Traumatic Defects And Face Deformations: Features Of Diagnostics And Treatment. The American Journal of Medical Sciences and Pharmaceutical Research. 2021;3(01):55-66.

https://doi.org/10.37547/TAJMSPR/Volume03Issue01-09

Kondo T, Kanayama K, Egusa H, Nishimura I. Current perspectives of residual ridge resorption: Pathological activation of oral barrier osteoclasts. Journal of Prosthodontic Research. 2023;67(1):12-22.

https://doi.org/10.2186/jpr.JPR_D_21_00333

PMid:35185111

MacBeth ND, Donos N, Mardas N. Alveolar ridge preservation with guided bone regeneration or socket seal technique A randomised, single‐blind controlled clinical trial. Clinical Oral Implants Research. 2022;33(7):681-99.

https://doi.org/10.1111/clr.13933

PMid:35488477 PMCid:PMC9541021

Clementini M, Morlupi A, Canullo L, Agrestini C, Barlattani A. Success rate of dental implants inserted in horizontal and vertical guided bone regenerated areas: a systematic review. International Journal of Oral and Maxillofacial Surgery. 2012;41(7):847-52.

https://doi.org/10.1016/j.ijom.2012.03.016

PMid:22542079

Arnal HM, Angioni CD, Gaultier F, Urbinelli R, Urban IA. Horizontal guided bone regeneration on knife‐edge ridges: A retrospective case-control pilot study comparing two surgical techniques. Clinical Implant Dentistry and Related Research. 2022;24(2):211-21.

https://doi.org/10.1111/cid.13073

PMid:35167184

Tay JRH, Ng E, Lu XJ, Lai WMC. Healing complications and their detrimental effects on bone gain in vertical‐guided bone regeneration: A systematic review and meta‐analysis. Clinical Implant Dentistry and Related Research. 2022;24(1):43-71.

https://doi.org/10.1111/cid.13057

PMid:35048503

Lie SAN, Claessen RMMA, Leung CAW, Merten HA, Kessler PAWH. Non-grafted versus grafted sinus lift procedures for implantation in the atrophic maxilla: a systematic review and meta-analysis of randomized controlled trials. International Journal of Oral and Maxillofacial Surgery. 2022;51(1):122-32.

https://doi.org/10.1016/j.ijom.2021.03.016

PMid:33849784

Rocchietta I, Moreno F, Nisand D. Management of Complications in Anterior Maxilla During Guided Bone Regeneration Bone Augmentation by Anatomical Region. USA: WILY. 2020;:235-54.

https://doi.org/10.1002/9781119427926.ch13

Cucchi A, Sartori M, Parrilli A, Aldini NN, Vignudelli E, Corinaldesi G. Histological and histomorphometric analysis of bone tissue after guided bone regeneration with non‐resorbable membranes vs resorbable membranes and titanium mesh. Clinical Implant Dentistry and Related Research. 2019;21(4):693-701.

https://doi.org/10.1111/cid.12814

PMid:31286649

Fugazzotto PA. Maintenance of Soft Tissue Closure Following Guided Bone Regeneration: Technical Considerations and Report of 723 Cases. Journal of Periodontology. 1999;70(9):1085-97.

https://doi.org/10.1902/jop.1999.70.9.1085

PMid:10505812

Windisch P, Orban K, Salvi GE, Sculean A, Molnar B. Vertical-guided bone regeneration with a titanium-reinforced d-PTFE membrane utilizing a novel split-thickness flap design: a prospective case series. Clinical Oral Investigations. 2020;25(5):2969-80.

https://doi.org/10.1007/s00784-020-03617-6

PMid:33040203 PMCid:PMC8060182

Mijiritsky E, Ferroni L, Gardin C, Bressan E, Zanette G, Piattelli A et al. Porcine Bone Scaffolds Adsorb Growth Factors Secreted by MSCs and Improve Bone Tissue Repair. Materials. 2017;10(9):1054.

https://doi.org/10.3390/ma10091054

PMid:28885576 PMCid:PMC5615709

Khojasteh A, Kheiri L, Motamedian S, Khoshkam V. Guided bone regeneration for the reconstruction of alveolar bone defects. Annals of Maxillofacial Surgery. 2017;7(2):263-77.

https://doi.org/10.4103/ams.ams_76_17

PMid:29264297 PMCid:PMC5717906

De Angelis P, Manicone P, De Angelis S, Passarelli P, Desantis V, Romeo A et al. Implant Placement with Simultaneous Guided Bone Regeneration Using Advanced Platelet-Rich Fibrin and a Deproteinized Bovine Bone Mineral: A 2-Year Retrospective and Comparative Study. The International Journal of Periodontics & Restorative Dentistry. 2022;42(6):e209-e16.

https://doi.org/10.11607/prd.5414

PMid:36305938

Naenni N, Stucki L, Hüsler J, Schneider D, Hämmerle CHF, Jung RE et al. Implants sites with concomitant bone regeneration using a resorbable or non-resorbable membrane result in stable marginal bone levels and similar profilometric outcomes over 5 years. Clin Oral Impl Res. 2021;32(8):893-904.

https://doi.org/10.1111/clr.13764

PMid:33977571

Jiang X, Zhang Y, Di P, Lin Y. Hard tissue volume stability of guided bone regeneration during the healing stage in the anterior maxilla: A clinical and radiographic study. Clinical Implant Dentistry and Related Research. 2017;20(1):68-75.

https://doi.org/10.1111/cid.12570

PMid:29283207

Pinheiro MPF, Quinelato V, Moreno MD, Pinheiro CC, Duarte JGR, Mesquita HdS et al. Predictability of osseointegrated implants installed in guided bone regeneration areas: a retrospective study. Revista Eletrônica Acervo Saúde. 2023;23(5): e11934.

https://doi.org/10.25248/reas.e11934.2023

Jung RE, Fenner N, Hämmerle CHF, Zitzmann NU. Long‐term outcome of implants placed with guided bone regeneration (GBR) using resorbable and non‐resorbable membranes after 12-14 years. Clinical Oral Implants Research. 2012;24(10):1065-73.

https://doi.org/10.1111/j.1600-0501.2012.02522.x

PMid:22697628

Bazrafshan N, Darby I. Retrospective success and survival rates of dental implants placed with simultaneous bone augmentation in partially edentulous patients. Clinical Oral Implants Research. 2013;25(7):768-73.

https://doi.org/10.1111/clr.12185

PMid:23647237

Cairo F, Nieri M, Cavalcanti R, Landi L, Rupe A, Sforza NM et al. Marginal soft tissue recession after lateral guided bone regeneration at implant site: A long‐term study with at least 5 years of loading. Clinical Oral Implants Research. 2020;31(11):1116-24.

https://doi.org/10.1111/clr.13658

PMid:32875633

Roca-Millan E, Jané-Salas E, Estrugo-Devesa A, López-López J. Evaluation of Bone Gain and Complication Rates after Guided Bone Regeneration with Titanium Foils: A Systematic Review. Materials. 2020;13(23):5346.

https://doi.org/10.3390/ma13235346

PMid:33255825 PMCid:PMC7728364

Arunjaroensuk S, Thunyakitpisal P, Nampuksa K, Monmaturapoj N, Mattheos N, Pimkhaokham A. Stability of guided bone regeneration with two ratios of biphasic calcium phosphate at implant sites in the esthetic zone: A randomized controlled clinical trial. Clinical Oral Implants Research. 2023;34(8):850-62.

https://doi.org/10.1111/clr.14113

PMid:37314107

Johnson TB, Siderits B, Nye S, Jeong Y-H, Han S-H, Rhyu I-C et al. Effect of guided bone regeneration on bone quality surrounding dental implants. Journal of Biomechanics. 2018;80:166-70.

https://doi.org/10.1016/j.jbiomech.2018.08.011

PMid:30170838 PMCid:PMC6233303

Dahlin C, Simion M, Hatano N. Long‐Term Follow‐Up on Soft and Hard Tissue Levels Following Guided Bone Regeneration Treatment in Combination with a Xenogeneic Filling Material: A 5‐Year Prospective Clinical Study. Clinical Implant Dentistry and Related Research. 2010;12(4):263-70.

https://doi.org/10.1111/j.1708-8208.2009.00163.x

PMid:19438941

Calciolari E, Corbella S, Gkranias N, Viganó M, Sculean A, Donos N. Efficacy of biomaterials for lateral bone augmentation performed with guided bone regeneration A network meta‐analysis. Periodontology 2000. 2023;93(1):77-106.

https://doi.org/10.1111/prd.12531

PMid:37752820

Esteves MET, Bianchini RMG, Gonzatti JPP, Scriboni AB. Guided bone regeneration in implant dentistry: a systematic review. MedNEXT Journal of Medical and Health Sciences. 2023;4(S2):mdnt23S221.

https://doi.org/10.54448/mdnt23S221

Dellavia C, Canciani E, Pellegrini G, Tommasato G, Graziano D, Chiapasco M. Histological assessment of mandibular bone tissue after guided bone regeneration with customized computer‐aided design/computer‐assisted manufacture titanium mesh in humans: A cohort study. Clinical Implant Dentistry and Related Research. 2021;23(4):600-11.

https://doi.org/10.1111/cid.13025

PMid:34139056

Abu Alfaraj T, Al-Madani S, Alqahtani NS, Almohammadi AA, Alqahtani AM, AlQabbani HS et al. Optimizing Osseointegration in Dental Implantology: A Cross-Disciplinary Review of Current and Emerging Strategies. Cureus. 2023;15(10):e47943.

https://doi.org/10.7759/cureus.47943

PMid:38034153 PMCid:PMC10685082

Wang C-W, Di Gianfilippo R, Kaciroti N, Ou A, Feng S-W, Wang H-L. Stability of peri-implantitis surgical reconstructive therapy-a (> 2 years) follow-up of a randomized clinical trial. Clinical Oral Investigations. 2023;28(1):30.

https://doi.org/10.1007/s00784-023-05457-6

PMid:38147180

Urban IA, Monje A, Lozada JL, Wang HL. Long‐term Evaluation of Peri‐implant Bone Level after Reconstruction of Severely Atrophic Edentulous Maxilla via Vertical and Horizontal Guided Bone Regeneration in Combination with Sinus Augmentation: A Case Series with 1 to 15 Years of Loading. Clinical Implant Dentistry and Related Research. 2016;19(1):46-55.

https://doi.org/10.1111/cid.12431

PMid:27238406

Win KZ, Pimkhaokham A, Kaboosaya B. Comparing Bone Graft Success, Implant Survival Rate, and Marginal Bone Loss: A Retrospective Study on Materials and Influential Factors. Journal of Oral Implantology. 2024;50(4):300-7.

https://doi.org/10.1563/aaid-joi-D-23-00165

PMid:38686547

Albrektsson T, Chrcanovic B, Östman PO, Sennerby L. Initial and long‐term crestal bone responses to modern dental implants. Periodontology 2000. 2016;73(1):41-50.

https://doi.org/10.1111/prd.12176

PMid:28000272

Zelikman H, Slutzkey G, Rosner O, Levartovsky S, Matalon S, Beitlitum I. Bacterial Growth on Three Non-Resorbable Polytetrafluoroethylene (PTFE) Membranes-An In Vitro Study. Materials. 2022;15(16):5705.

https://doi.org/10.3390/ma15165705

PMid:36013840 PMCid:PMC9414989

Garcia J, Dodge A, Luepke P, Wang HL, Kapila Y, Lin GH. Effect of membrane exposure on guided bone regeneration: A systematic review and meta‐analysis. Clinical Oral Implants Research. 2018;29(3):328-38.

https://doi.org/10.1111/clr.13121

PMid:29368353

Michal Halperin-Sternfeld HZ-G, Lior Shapira, Asaf Wilensky. Lateral Guided Bone Regeneration Using a Novel Synthetic Bioresorbable Membrane: A Two Center Prospective Randomized Controlled Trial. Journal of Molecular and Clinical Medicine. 2018;1(3):169-76.

https://doi.org/10.31083/j.jmcm.2018.03.006

Yankov YG. Socket Preservation and Guided Bone Regeneration: Prerequisites for Successful Implant Dentistry. Cureus. 2023;15(11):e48785.

https://doi.org/10.7759/cureus.48785

Robert L, Aloy-Prósper A, Arias-Herrera S. Vertical augmentation of the atrofic posterior mandibular ridges with onlay grafts: Intraoral blocks vs guided bone regeneration Systematic review. Journal of Clinical and Experimental Dentistry. 2023;15(5):e357-65.

https://doi.org/10.4317/jced.60294

PMid:37214750 PMCid:PMC10198694

Ramanauskaite A, Becker K, Cafferata EA, Schwarz F. Clinical efficacy of guided bone regeneration in peri‐implantitis defects A network meta‐analysis. Periodontology 2000. 2023;93(1):236-53.

https://doi.org/10.1111/prd.12510

PMid:37490412

Aprile P, Letourneur D, Simon‐Yarza T. Membranes for Guided Bone Regeneration: A Road from Bench to Bedside. Advanced Healthcare Materials. 2020;9(19):2000707.

https://doi.org/10.1002/adhm.202000707

PMid:32864879

Chouler J, Bentley I, Vaz F, O'Fee A, Cameron PJ, Di Lorenzo M. Exploring the use of cost-effective membrane materials for Microbial Fuel Cell based sensors. Electrochimica Acta. 2017;231:319-26.

https://doi.org/10.1016/j.electacta.2017.01.195

Jonker B, Wolvius E, van der Tas J, Tahmaseb A, Pijpe J. Esthetics and Patient-Reported Outcomes of Implants Placed with Guided Bone Regeneration and Complete Native Bone: A Prospective Controlled Clinical Trial. The International Journal of Oral & Maxillofacial Implants. 2020;35(2):406-14.

https://doi.org/10.11607/jomi.7751

PMid:32142578

Donos N, Akcali A, Padhye N, Sculean A, Calciolari E. Bone regeneration in implant dentistry: Which are the factors affecting the clinical outcome? Periodontology 2000. 2023;93(1):26-55.

https://doi.org/10.1111/prd.12518

PMid:37615306

Mandelli F, Traini T, Ghensi P. Customized-3D zirconia barriers for guided bone regeneration (GBR): clinical and histological findings from a proof-of-concept case series. Journal of Dentistry. 2021;114:103780.

https://doi.org/10.1016/j.jdent.2021.103780

PMid:34400253

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Published

2024-12-08

How to Cite

Taghizadeh , E., Negargar , S., Nuroozi Larki , K., Saberi Haghighi , R., & Shahoon , H. (2024). The Role of Guided Bone Regeneration in Enhancing Dental Implant Success: Guided Bone Regeneration in Dental Implant. Galen Medical Journal, 13(SP1), e3681. Retrieved from https://journals.salviapub.com/index.php/gmj/article/view/3681