Emerging Diagnostic Modalities in Oral Cancer Detection and Management

Modalities in Oral Cancer Detection and Management

Authors

  • Ashkan Badkoobeh Department of Oral and Maxillofacial Surgery, School of Dentistry, Qom University of Medical Sciences, Qom, Iran
  • Shadi Zarakhsh Faculty of Dentistry, Isfahan, Khorasgan Branch, Islamic Azad University, Isfahan, Iran
  • Mehrnaz Fayazi School of Dentistry, Islamic Azad University of Medical sciences, Tehran, Iran
  • Pouya Kavianpour Department of Endodontics, School of Dentistry, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
  • Zahra Bahman Faculty of Dentistry, Belarusian State Medical University, Belarus, Minsk
  • Maryam Onsori Department of Operative Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  • Mahsa Etemadi Department of Periodontology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran

DOI:

https://doi.org/10.31661/gmj.v13i.3423

Keywords:

Oral Cancer; Diagnostics; Salivary Biomarkers; Optical Imaging; Liquid Biopsy; PET-CT; MRI Spectroscopy; Artificial Intelligence; Early Detection; Personalized Medicine

Abstract

Oral cancer remains a significant global health concern, yet it is often detected at an advanced stage. The limitations of traditional diagnostic techniques have prompted increased research efforts towards the development of more efficient and early detection methods. Recent advancements in oral cancer diagnosis include the use of salivary biomarkers, optical imaging, liquid biopsy, advanced imaging, and AI algorithms. These non-invasive and painless sampling methods have shown high sensitivity and specificity, particularly in the case of salivary biomarkers. Clinical trials and cooperation are necessary to demonstrate the effectiveness of these technologies and gain approval from relevant authorities and acceptance among clinicians. This review highlights the potential of these new modalities in transforming the approach to oral cancer diagnosis, leading to early detection, accurate diagnosis, and quality treatment for patients, ultimately reducing the global burden of this disease.

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Published

2024-09-25

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Review Article