Treatment of Angiomyoblastoma in a Young Lady in Saudi Arabia: A Case Report and Literature Review

Abstract

 Background: Angiomyofibroblastoma (AMFB) is a rare, benign soft tissue tumor that belongs to the mesenchymal tumor category and affects the female genital tract. Aggressive angiomyxoma, a distinct stroma myxoedematous mesenchymal tumor with a significant risk of local recurrences, must be histomorphologically distinguished from AMFB. Radiography and histopathology are used for accurate diagnosis. The treatment depended on the complete surgical excision.

Case presentation: Herein, we presented a case of a 36-year-old female (P3+0) presented with a left vaginal mass noted two years prior. The radiology report suggested angiomyxoma or myxoid liposarcoma as possible differentials. Surgical resection revealed a benign genital stromal tumor, specifically angiomyofibroblastoma (AMFB). After complete surgical excision, the immunohistochemical analysis supported the diagnosis of angiomyofibroblastoma. Two months postoperatively, an MRI Post-resection images show complete resection with no feasible scar, residual tumor, or recurrence.

Conclusion: Our case is rare AMFB. AMFB may be missed when diagnosed with other masses, such as angiomyxoma or myxoid liposarcoma, so we need to do the necessary tests to diagnose and differentiate AMFB accurately from other masses. Ultrasound and MRI are initial diagnostic tools, while histopathology ensures the correct diagnosis. Surgical removal with free margins remains the appropriate treatment. Long-term follow-up is essential to monitor for potential recurrence, though AMFB typically carries an excellent prognosis.