The Quality of Life beafore and after Hysterectomy in Premenopausal Women
Keywords:
Hysterectomy; Perimenopause; Quality of life; SF-36Abstract
Background: Hysterectomy in premenopausal women has become very common due to the presence of benign disorders of the reproductive system. The present study was conducted as a longitudinal prospective cohort study to evaluate the quality of life before and after hysterectomy in premenopausal women, assessed at 3, 6, and 12 months postoperatively. Materials and Methods: This longitudinal prospective cohort study was conducted on 130 women aged 35–50 years who underwent hysterectomy with ovarian preservation in Amiralmomenin Hospital of Semnan, Iran. Data were collected before the operation, three months, six months, and one year after the hysterectomy using demographic characteristics and a standard quality of life questionnaire (SF-36). Data were analyzed using SPSS 22 software (P<0.05). Results: In the present study, 28 patients (21.5%) were ≤40 years old and 102 (78.5%) were ≥40 years old. A significant increase was observed in the scores of quality of life, physical health, mental health, and general health (P≥0.001). However, there was no significant difference in physical and mental function. Also, there was no relationship between quality of life and demographic characteristics (age, marital status, education, underlying disease, number of children, and number of deliveries). This is while postoperative complications and employment had a significant relationship with the quality of life (P≥0.001). Conclusion: In the present study, the quality of life was improved one year after hysterectomy with ovarian preservation.
References
Adam EE, White MC, Saraiya M. US hysterectomy prevalence by age, race and ethnicity from BRFSS and NHIS: implications for analyses of cervical and uterine cancer rates. Cancer Causes & Control. 2022 Jan 1:16.
https://doi.org/10.1007/s10552-021-01496-0
PMid:34546462 PMCid:PMC8738136
Lycke KD, Kahlert J, Damgaard R, Mogensen O, Hammer A. Trends in hysterectomy incidence rates during 2000-2015 in Denmark: shifting from abdominal to minimally invasive surgical procedures. Clinical epidemiology. 2021 Jun 1:40716.
https://doi.org/10.2147/CLEP.S300394
PMid:34103999 PMCid:PMC8180274
Simms KT, Yuill S, Killen J, Smith MA, Kulasingam S, de Kok IM, van Ballegooijen M, Burger EA, Regan C, Kim JJ, Canfell K. Historical and projected hysterectomy rates in the USA: implications for future observed cervical cancer rates and evaluating prevention interventions. Gynecologic oncology. 2020 Sep 1;158(3):710-8.
https://doi.org/10.1016/j.ygyno.2020.05.030
PMid:32723676 PMCid:PMC8723888
LaughlinTommaso SK, Khan Z, Weaver AL, Smith CY, Rocca WA, Stewart EA. Cardiovascular and metabolic morbidity after hysterectomy with ovarian conservation: a cohort study. Menopause. 2018 May 1;25(5):48392.
https://doi.org/10.1097/GME.0000000000001043
PMid:29286988 PMCid:PMC5898981
Nicholson WK, Wegienka G, Zhang S, Wallace K, Stewart E, LaughlinTommaso S, Thomas L, Jacoby VL, Marsh EE, Wise L, Borah BJ. Shortterm healthrelated quality of life after hysterectomy compared with myomectomy for symptomatic leiomyomas. Obstetrics & Gynecology. 2019 Aug 1;134(2):2619.
https://doi.org/10.1097/AOG.0000000000003354
PMid:31306318 PMCid:PMC8579313
Bougie O, Suen MW, Pudwell J, MacGregor B, Plante S, Nitsch R, Singh SS. Evaluating the prevalence of regret with the decision to proceed with a hysterectomy in women younger than age 35. Journal of Obstetrics and Gynaecology Canada. 2020 Mar 1;42(3):2628.
https://doi.org/10.1016/j.jogc.2019.08.006
PMid:31734156
Kök G, Erdoğan EN, Söylemez EB, Güvenç G. Histerektomi olan hastanın fonksiyonel sağlık örüntülerine göre hemşirelik bakımı: Olgu sunumu. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi. 2020;11(2):2738.
Korstjens I, Moser A. Series: Practical guidance to qualitative research Part 4: Trustworthiness and publishing. European Journal of General Practice. 2018 Jan 1;24(1):1204.
https://doi.org/10.1080/13814788.2017.1375092
PMid:29202616 PMCid:PMC8816392
Lee SH, Oh SR, Cho YJ, Han M, Park JW, Kim SJ, Yun JH, Choe SY, Choi JS, Bae JW. Comparison of vaginal hysterectomy and laparoscopic hysterectomy: a systematic review and metaanalysis. BMC women's health. 2019 Dec;19:12.
https://doi.org/10.1186/s12905-019-0784-4
PMid:31234852 PMCid:PMC6591934
Bhandari P. Stress and health related quality of life of Nepalese students studying in South Korea: A cross sectional study. Health and quality of life outcomes. 2012 Dec;10:19.
https://doi.org/10.1186/1477-7525-10-26
PMid:22410138 PMCid:PMC3334675
Haghpanah S, Nasirabadi S, Ghaffarpasand F, Karami R, Mahmoodi M, Parand S, Karimi M. Quality of life among Iranian patients with betathalassemia major using the SF36 questionnaire. Sao Paulo medical journal. 2013;131(3):16672.
https://doi.org/10.1590/1516-3180.2013.1313470
PMid:23903265 PMCid:PMC10852107
Raeisi D, Omrani HR, Seyedzadeh A, Akbari R, Tavasoli M, SafariFaramani R. Quality of Life and It's Determinant in hemodialysis patients in Kermanshah in 2010. Journal of Kermanshah University of medical sciences. 2013 Mar 30;16(8):123-130.
Wright JD, Herzog TJ, Tsui J, Ananth CV, Lewin SN, Lu YS, Neugut AI, Hershman DL. Nationwide trends in the performance of inpatient hysterectomy in the United States. Obstetrics & Gynecology. 2013 Aug 1;122(2 PART 1):23341.
https://doi.org/10.1097/AOG.0b013e318299a6cf
PMid:23969789 PMCid:PMC3913114
Moen M, Noone M, CholkeriSingh A, Vassallo B, Locker B, Miller C. Progressive reduction in abdominal hysterectomy rates: impact of laparoscopy, robotics and surgeon factors. Journal of robotic surgery. 2014 Mar;8:137.
https://doi.org/10.1007/s11701-013-0412-5
PMid:27637233
Maheri A, Sadeghi R, Shojaeizadeh D, Tol A, Yaseri M, Ebrahimi M. Associations between a health-promoting lifestyle and quality of life among adults with beta-thalassemia major. Epidemiology and health. 2016 Nov 15;38:e2016050.
https://doi.org/10.4178/epih.e2016050
PMid:27857026 PMCid:PMC5177799
El-Habashi AF, El-Agroudy AE, Jaradat A, Alnasser ZH, Almajrafi HH, Alharbi RH, Alanzy A, Alqahtani AM. Quality of life and its determinants among hemodialysis patients: A single-center study. Saudi Journal of Kidney Diseases and Transplantation. 2020 Mar 1;31(2):460-72.
https://doi.org/10.4103/1319-2442.284022
PMid:32394920
Zhan TT, Wang LL, Wang Y, Sun CJ. Master of nursing specialist experiences of an internship through the use of written reflections: A qualitative research study. Heliyon. 2023 Feb 1;9(2):e13299.
https://doi.org/10.1016/j.heliyon.2023.e13299
PMid:36814604 PMCid:PMC9939592
Till SR, Schrepf A, Pierce J, Moser S, Kolarik E, Brummett C, AsSanie S. Sexual function after hysterectomy according to surgical indication: a prospective cohort study. Sexual health. 2022 Mar 1;19(1):4654.
https://doi.org/10.1071/SH21153
PMid:35226836 PMCid:PMC9297198
LaughlinTommaso SK, Satish A, Khan Z, Smith CY, Rocca WA, Stewart EA. Longterm risk of de novo mental health conditions after hysterectomy with ovarian conservation: a cohort study. Menopause. 2020 Jan 1;27(1):3342.
https://doi.org/10.1097/GME.0000000000001415
PMid:31479034 PMCid:PMC7089568
Zimmermann JS, Sima RM, Radosa MP, Radosa CG, Ples L, Wagenpfeil S, Solomayer EF, Radosa JC. Quality of life and sexual function in patients aged 35 years or younger undergoing hysterectomy for benign gynecologic conditions: A prospective cohort study. International Journal of Gynecology & Obstetrics. 2023 Feb;160(2):54853.
https://doi.org/10.1002/ijgo.14400
PMid:35965372
Ferhi M, Marwen N, Abdeljabbar A, Mannai J. Psychological Outcomes and Quality of Life After Hysterectomy for Benign Diseases: A Prospective Cohort Study. Cureus. 2024 May 22;16(5): e60871.
https://doi.org/10.7759/cureus.60871
Oxley S, Xiong R, Wei X, Kalra A, Sideris M, Legood R, Manchanda R. Quality of Life after RiskReducing Hysterectomy for Endometrial Cancer Prevention: A Systematic Review. Cancers. 2022 Nov 26;14(23):5832.
https://doi.org/10.3390/cancers14235832
PMid:36497314 PMCid:PMC9736914
Moorman PG, Schildkraut JM, Myers ER, Wang F. Reported symptoms before and one year after hysterectomy in African American and white women. Journal of Women's Health. 2011 Jul 1;20(7):103542.
https://doi.org/10.1089/jwh.2010.2543
PMid:21671769 PMCid:PMC3130512
Bahri N, Tohidinik HR, Najafi TF, Larki M, Amini T, Sartavosi ZA. Depression following hysterectomy and the influencing factors. Iranian Red Crescent Medical Journal. 2016 Jan;18(1): e30493.
https://doi.org/10.5812/ircmj.30493
Borimnejad L, Mohadeth Ardebili F, Jozee Kabiri F, Haghani H. Comparison of quality of life after hysterectomy in pre and post menopause period in Iranian women. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2011 Jan 21;13(6):3945.
Daugbjerg SB, Cesaroni G, Ottesen B, Diderichsen F, Osler M. Effect of socioeconomic position on patient outcome after hysterectomy. Acta obstetricia et gynecologica Scandinavica. 2014 Sep;93(9):92634.
https://doi.org/10.1111/aogs.12444
PMid:24957782
LaughlinTommaso SK, Satish A, Khan Z, Smith CY, Rocca WA, Stewart EA. Longterm risk of de novo mental health conditions after hysterectomy with ovarian conservation: a cohort study. Menopause. 2020 Jan 1;27(1):3342.
https://doi.org/10.1097/GME.0000000000001415
PMid:31479034 PMCid:PMC7089568
Altman D, Yin L, Johansson A, Lundholm C, Grönberg H. Risk of renal cell carcinoma after hysterectomy. Archives of internal medicine. 2010 Dec 13;170(22):20116.
https://doi.org/10.1001/archinternmed.2010.425
PMid:21149759
Luo J, Hendryx M, Manson JE, Liang X, Margolis KL. Hysterectomy, oophorectomy, and risk of thyroid cancer. The Journal of Clinical Endocrinology & Metabolism. 2016 Oct 1;101(10):38129.
https://doi.org/10.1210/jc.2016-2011
PMid:27459531 PMCid:PMC5052349
ClarkePearson DL, Geller EJ. Complicaciones de la histerectomía. Obstet Gynecol. 2013;121(3):128.
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