Effect of traditional Chinese medicine external treatment in older patients with nocturia: a meta-analysis
DOI:
https://doi.org/10.31661/gmj.v15i.3986Keywords:
Traditional Chinese Medicine External Treatment; Conventional Western Medicine Treatment; Nocturia; Pittsburgh Sleep Quality Index; Response RateAbstract
Aim: To assess the efficacy and clinical value of traditional Chinese medicine external treatment (TCMET) for older patients with nocturia.
Methods: A systematic search was conducted in PubMed, Embase, Cochrane Library, Chinese National KnowledgeInfrastructure (CNKI), Chinese Biological Medicine Database (CBM), VIP Chinese Science and Technology Journal Full-text Database (VP-CSJFD), and Wanfang database from their inception to September 30, 2024. Studies focusing on applying TCMET for older patients with nocturia were included. Primary outcome measures comprised the times of nocturia, Pittsburgh sleep quality index (PSQI) scores, and overall response rate. The extracted data was analyzed using Stata software (Version 17.0).
Results: 15 articles were included in this study, including 580 patients in the TCMET group and 318 patients in the conventional western medicine treatment (CWMT) group. The overall response rate after TCMET treatment in patients with nocturia was 94% [ES = 0.94, 95%CI (0.91, 0.94)]. The number of nocturia episodes after treatment decreased by 2.39 times compared to before treatment [SMD = 2.39, 95% CI (1.30, 3.48)]. TCMET treatment resulted in a 4.77-point decrease in patients’ PSQI scores from baseline [SMD =4.77, 95% CI: 1.67, 7.86]. Compared with CWMT, TCMET did not show significant superiority improve overall response rate and PSQI score (P > 0.05) but reduced the number of nocturia after TCMET treatment [SMD = -2.03, 95%CI (-3.15, -0.91), P < 0.05].
Conclusion: According to the existing literature evidence, TCMET can reduce the times of nocturia and improve sleep quality in older patients with nocturia. It is an effective treatment for older patients with nocturia.
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