Evaluation of Morphological Changes in Breast Cancer: Influence of Fractal Meta-Analysis

Authors

  • SeyedAbbas Mirmalek Assistant Professor of General Surgery, Azad University of Medical Sciences and Health Services, Boali Hospital, Tehran, Iran
  • Niloofar sadat Yarandi General Practitioner, Azad University of Medical Sciences and Health Services, Boali Hospital, Tehran, Iran
  • Mohammad Tafazoli Shadpour Biomedical Engineering, Amirkabir University, Tehran, Iran
  • Minoo Saatian Pathologist, Azad University of Medical Sciences and Health Services, Boali Hospital, Tehran, Iran
  • Homa Raeesi Pathologist, Kasra Hospital, Tehran, Iran
  • Esmaieel Jafargholi Rangraz Biomedical Engineering, Amirkabir University, Tehran, Iran
  • Masoud Salehi Assistant Professor of Biostatistics, Department of Biostatistics, Faculty of Management and Medical Informatics, Tehran University of Medical Sciences, Tehran, Iran
  • Seyed Alireza Salimi Tabatabaee Medical Student, Islamic Azad University, Tehran Medical Branch, Tehran, Iran

DOI:

https://doi.org/10.31661/gmj.v3i2.233

Keywords:

Breast Cancer, Fractal Complex, Ductal Carcinoma, Prediction

Abstract

Many studies suggested that fractals could be brought in any structural anarchy, such as cancers, for diagnosis and prognosis evaluation by quantifying it and expressing it in terms of fractal geometry. In this study, we aimed to evaluate pathologic grades or breast carcinomas by fractal analysis. This cross-sectional study was performed on 60 women with breast ductal carcinoma. From all the patients some photographs from the smears with pathological standard and with a digital camera were taken to analyze them by MATLAB software via Box-Counting method. The used analytical methods were ANOVA and T tests. There was a significant association between fractal count and the pathological grade (P<0.05). According to the findings of this study, fractal count was a prognostic indicator in breast cancer patients. However, we recommended performing further studies with higher sample size and in other types of cancers.

Published

2014-05-25

How to Cite

Mirmalek, S., Yarandi, N. sadat, Tafazoli Shadpour, M., Saatian, M., Raeesi, H., Jafargholi Rangraz, E., … Salimi Tabatabaee, S. A. (2014). Evaluation of Morphological Changes in Breast Cancer: Influence of Fractal Meta-Analysis: . Galen Medical Journal, 3(2), e233. https://doi.org/10.31661/gmj.v3i2.233

Issue

Section

Letter to Editor