Association between Elevated TNF-α Levels and Severe Malaria

TNF-α Levels and Severe Malaria

Authors

  • Khalid Mohamedahmed Department of Hematology and Immunohematology, Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan/ Department of Hematology and Immunology, Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan

DOI:

https://doi.org/10.31661/gmj.v12i.2927

Keywords:

TNF-α, Severe Malaria, Proinflammatory Cytokine

Abstract

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References

Daffa Alla N, Sukkar MY. IFN-γ, TNF-α and IL-10 responses in children infected with malaria parasite. Khartoum Med J. 2015; 8(3):1143-1152. Mohamedahmed KA; Abakar AD; Ahmed MO; Mukhtar MM; Nour BYM. The Role of TNF-α Levels as Predictive Diagnostic Biomarker Among Children with Severe Falciparum Malaria in Endemic Area in Sudan. IJAHMR. 2019;3(7):1-6. Sinha S, Mishra SK, Sharma S, Patibandla PK, Mallick PK, Sharma SK, et al. Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population. Malar J. 2008;7:13. https://doi.org/10.1186/1475-2875-7-13PMid:18194515 PMCid:PMC2245971 Thuma PE, van Dijk J, Bucala R, Debebe Z, Nekhai S, Kuddo T, et al. Distinct clinical and immunologic profiles in severe malarial anemia and cerebral malaria in Zambia. J Infect Dis. 2011;203(2):211-9. https://doi.org/10.1093/infdis/jiq041PMid:21288821 PMCid:PMC3071068 Deroost K, Pham TT, Opdenakker G, Van den Steen PE. The immunological balance between host and parasite in malaria. FEMS Microbiol Rev. 2016;40(2):208-57. https://doi.org/10.1093/femsre/fuv046PMid:26657789 Wammes LJ, Wiria AE, Toenhake CG, Hamid F, Liu KY, Suryani H et al. Asymptomatic plasmodial infection is associated with increased tumor necrosis factor receptor II-expressing regulatory T cells and suppressed type 2 immune responses. J Infect Dis. 2013;207(10):1590-1599. https://doi.org/10.1093/infdis/jit058PMid:23408847 Cabantous S, Doumbo O, Ranque S, Poudiougou B, Traore A, Hou X, et al. Alleles 308A and 238A in the tumor necrosis factor alpha gene promoter do not increase the risk of severe malaria in children with Plasmodium falciparum infection in Mali. Infect Immun. 2006;74(12):7040-7042. https://doi.org/10.1128/IAI.01581-05PMid:16982833 PMCid:PMC1698072 Ekvall H. Malaria and anemia. Curr Opin Hematol. 2003;10(2):108-114. https://doi.org/10.1097/00062752-200303000-00002PMid:12579035 Dodoo D; Omer FM; Todd J; Akanmori BD; Koram KA; Riley EM. Absolute Levels and Ratios of Proinflammatory and Anti-inflammatory Cytokine Production In Vitro Predict Clinical Immunity to Plasmodium falciparum Malaria. J Infect Dis. 2002;185(7):971-9. https://doi.org/10.1086/339408PMid:11920322 Flori L; Delahaye NF; Iraqi FA; Hernandez-Valladares M; Fumoux F; Rihet P. TNF as a malaria candidate gene: polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso. Genes and Immun. 2005;6(6):472-480. https://doi.org/10.1038/sj.gene.6364231PMid:15931230

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Published

2023-04-25

Issue

Vol. 12 (2023): 2023

Section

Letter to Editor

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