Evaluation of the Effect of Silver Diamine Fluoride Treatment with and without Glutathione and Potassium Iodide on the Micro-Shear Bond Strength of Composite Resin to Primary Tooth Dentin

Authors

  • Alireza Mohammadzadeh Shabestari Department of Dental Surgery, Mashhad University of Medical Sciences, Mashhad, Iran

Keywords:

Keywords Tumor necrosis factor-alpha (TNF-α); Matrix metalloproteinase (MMP); Peri-implantitis.

Abstract

Background: The present study was designed and conducted to determine the effect of silver diamine fluoride (SDF) treatment, with and without glutathione and potassium iodide, on the micro-shear bond strength of composite resin to primary tooth dentin. Materials and Methods: An in vitro experimental design was used with 52 sound extracted primary teeth randomly divided into four groups (n = 13): (a) control (no SDF), (b) SDF, (c) SDF+KI, and (d) SDF+GSH. Demineralized dentin was prepared and treated per group protocol. All samples received total-etch adhesive (Single Bond 2) and Z250 composite resin restorations. Micro-shear bond strength was measured using a universal testing machine at a crosshead speed of 1 mm/min until failure. Data were analyzed using one-way ANOVA and Tukey post hoc tests (α = .05). Results: Significant differences in mean μSBS were observed among groups, F(3, 48) = 14.27, p < .001. The control group demonstrated the lowest bond strength (8.24 ± 1.31 MPa), whereas the SDF (15.34 ± 3.72 MPa), SDF+KI (14.68 ± 3.96 MPa), and SDF+GSH (14.51 ± 2.97 MPa) groups exhibited significantly higher values (P < .001 for all vs. control). No significant differences were found among the SDF-treated groups (P > .90). Conclusion: Given that the application of SDF, SDF combined with glutathione, and SDF treatment with potassium iodide before composite restoration enhances bond strength, it is recommended to use these treatments.

Published

2025-12-16

How to Cite

Mohammadzadeh Shabestari , A. (2025). Evaluation of the Effect of Silver Diamine Fluoride Treatment with and without Glutathione and Potassium Iodide on the Micro-Shear Bond Strength of Composite Resin to Primary Tooth Dentin. Galen Medical Journal, e3898. Retrieved from https://journals.salviapub.com/index.php/gmj/article/view/3898

Issue

Section

Review Article